The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 2020

Filed:

Apr. 11, 2017
Applicant:

Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.l.a. China, Beijing, CN;

Inventors:

Song Li, Beijing, CN;

Xinbo Zhou, Beijing, CN;

Dian Xiao, Beijing, CN;

Wu Zhong, Beijing, CN;

Junhai Xiao, Beijing, CN;

Zhibing Zheng, Beijing, CN;

Xingzhou Li, Beijing, CN;

Yunde Xie, Beijing, CN;

Xiaokui Wang, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 13/04 (2006.01); C07D 413/12 (2006.01); C07D 271/12 (2006.01); A61P 11/00 (2006.01); A61P 25/28 (2006.01); C07H 1/00 (2006.01); A61K 31/7056 (2006.01); A61K 31/4245 (2006.01);
U.S. Cl.
CPC ...
C07H 13/04 (2013.01); A61K 31/4245 (2013.01); A61K 31/7056 (2013.01); A61P 11/00 (2018.01); A61P 25/28 (2018.01); C07D 271/12 (2013.01); C07D 413/12 (2013.01); C07H 1/00 (2013.01);
Abstract

Disclosed in the present invention is a compound of Formula (I), a geometric or optical isomer, a pharmaceutically acceptable salt, a solvate or a polymorph thereof. Also disclosed in the present invention is a composition comprising the compound of Formula (I), the geometric or optical isomer, the pharmaceutically acceptable salt, the solvate or the polymorph thereof. Also disclosed in the present invention is a use of the compound of Formula (I), the geometric or optical isomer, the pharmaceutically acceptable salt, the solvate or the polymorph thereof in the treatment of a disease or disorder such as a hypoglutamatergic condition, a neurodegenerative disease or respiratory depression, particularly in the treatment of a disease or disorder associated with AMPA receptor.


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