The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 2020

Filed:

Apr. 06, 2017
Applicant:

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

Shaomeng Wang, Superior Township, MI (US);

Yangbing Li, Ann Arbor, MI (US);

Angelo Aguilar, Ann Arbor, MI (US);

Bing Zhou, Ann Arbor, MI (US);

Jiantao Hu, Ann Arbor, MI (US);

Fuming Xu, Ypsilanti, MI (US);

Chong Qin, Ann Arbor, MI (US);

Yang Hu, Ann Arbor, MI (US);

Weiguo Xiang, Ypsilanti, MI (US);

Rohan Rej, Ann Arbor, MI (US);

Jiuling Yang, Ann Arbor, MI (US);

Xin Han, Ann Arbor, MI (US);

Longchuan Bai, Ann Arbor, MI (US);

Chao-Yie Yang, Ann Arbor, MI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 487/10 (2006.01); C07D 401/14 (2006.01); C07D 487/04 (2006.01); C07D 495/14 (2006.01);
U.S. Cl.
CPC ...
C07D 487/10 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 487/04 (2013.01); C07D 495/14 (2013.01);
Abstract

The present disclosure provides compounds represented by Formula I: and the salts or solvates thereof, wherein X, L, Y, and B are as defined in the specification. Compounds having Formula I are immunomodulators and/or monofunctional synthetic intermediates that can be used to prepare small-molecule drug conjugates.


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