The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 2020
Filed:
Dec. 27, 2018
Applicant:
Synchronicity Pharma, Inc., San Jose, CA (US);
Inventors:
Ross Bersot, Orinda, CA (US);
Paul Humphries, Santa Clara, CA (US);
Assignee:
Synchronicity Pharma, Inc., San Jose, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/454 (2006.01); A61K 31/513 (2006.01); A61K 31/403 (2006.01); A61K 31/5377 (2006.01); C07D 401/06 (2006.01); A61K 45/06 (2006.01); C07D 403/06 (2006.01); C07D 413/06 (2006.01); C12Q 1/6883 (2018.01); C07D 209/52 (2006.01);
U.S. Cl.
CPC ...
C07D 401/06 (2013.01); A61K 31/403 (2013.01); A61K 31/454 (2013.01); A61K 31/513 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 209/52 (2013.01); C07D 403/06 (2013.01); C07D 413/06 (2013.01); C12Q 1/6883 (2013.01); C12Q 2600/118 (2013.01); Y10T 436/143333 (2015.01);
Abstract
The subject matter herein is directed to carbazole-containing amide, carbamate, and urea derivatives and pharmaceutically acceptable salts or hydrates thereof of structural formula I wherein the variable R, R, R, R, R, R, R, A, D, E, G, J, L, M, Q, a, and b are accordingly described. Also provided are pharmaceutical compositions containing the compounds of formula I to treat a Cry-mediated disease or disorder, such as diabetes, complications associated with diabetes, Cushing's syndrome, NASH, NAFLD, asthma, and COPD.