The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 2020
Filed:
Oct. 17, 2014
Applicant:
President and Fellows of Harvard College, Cambridge, MA (US);
Inventors:
Tobias Ritter, Cambridge, MA (US);
Constanze Nicole Neumann, Somerville, MA (US);
Assignee:
President and Fellows of Harvard College, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 233/70 (2006.01); C07B 59/00 (2006.01); A61K 51/04 (2006.01); C07C 309/04 (2006.01); C07D 233/84 (2006.01);
U.S. Cl.
CPC ...
C07D 233/70 (2013.01); A61K 51/04 (2013.01); C07B 59/00 (2013.01); C07B 59/001 (2013.01); C07B 59/007 (2013.01); C07C 309/04 (2013.01); C07D 233/84 (2013.01); C07B 2200/05 (2013.01);
Abstract
Methods for fluorinating organic compounds utilizing a novel organic reagent are described herein. The invention further discloses the utility of this reagent for incorporation of the 18 F isotope into hydroxyl group-containing organic molecules for PET imaging studies. Preparation of the reagents is described along with isolable intermediate structures from reaction of the reagent with a hydroxyl group-containing organic molecule.