The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 2020
Filed:
Jun. 29, 2018
Chinoin Pharmaceutical and Chemical Works Private Co. Ltd., Budapest, HU;
Irén Hortobágyi, Budapest, HU;
István Lászlófi, Nagykálló, HU;
Zsuzsanna Kardos, Budapest, HU;
József Molnár, Biatorbágy, HU;
László Takács, Budapest, HU;
Kornélia Horváth, Budapest, HU;
Abstract
A process of preparing compounds of general formula I, by cuprate coupling of a vinyl cuprate of general formula II with a protected enone of general formula IV to produce a compound of general formula (V) removing the protecting groups of the compound of general formula (V) and purifying the compound of general formula (I) by chromatography; wherein the vinyl cuprate of formula (II) is prepared by reacting a vinyl stannane of formula III with copper halide CuX and alkyllithium R1Li and wherein an excess of the alkyllithium is decomposed before the said coupling reaction.