The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 2020

Filed:

Sep. 09, 2016
Applicant:

Polyactiva Pty Ltd, Melbourne, Victoria, AU;

Inventors:

Stephen Lonsdale Birkett, West Brunswick, AU;

Andrew Craig Donohue, Bentleigh East, AU;

Asha Marina D'Souza, Carnegie, AU;

Sarah Man Yee Ng, Berwick, AU;

Adrian Sulistio, Glen Iris, AU;

Russell John Tait, Balwyn, AU;

David Valade, Coburg North, AU;

Alan Naylor, Harston, GB;

Anton Blencowe, Windsor Gardens, AU;

Assignee:

POLYACTIVA PTY LTD, Melbourne, Victoria, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/50 (2017.01); A61K 31/4192 (2006.01); A61K 31/4196 (2006.01); A61K 31/47 (2006.01); A61K 31/19 (2006.01); A61K 47/59 (2017.01); A61K 31/196 (2006.01); A61K 47/60 (2017.01); A61K 31/496 (2006.01); A61K 31/407 (2006.01); A61K 31/192 (2006.01); A61K 31/606 (2006.01); A61K 31/635 (2006.01); A61P 29/00 (2006.01); A61K 31/60 (2006.01);
U.S. Cl.
CPC ...
A61K 47/595 (2017.08); A61K 31/192 (2013.01); A61K 31/196 (2013.01); A61K 31/407 (2013.01); A61K 31/496 (2013.01); A61K 31/606 (2013.01); A61K 31/635 (2013.01); A61K 47/60 (2017.08); A61K 31/47 (2013.01); A61K 31/60 (2013.01); A61K 2300/00 (2013.01); A61P 29/00 (2018.01);
Abstract

The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from quinolones, NSAIDs and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click cycloaddition chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the post-surgical care to treat or prevent infections, provide analgesia and treat inflammation.


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