The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 2020

Filed:

Jun. 24, 2016
Applicant:

University of Southern California, Los Angeles, CA (US);

Inventors:

Justin Ichida, Los Angeles, CA (US);

Shaoyu Lin, Monterey Park, CA (US);

Yichen Li, Oxford, GB;

Yingxiao Shi, Los Angeles, CA (US);

Assignee:

University of Southern California, Los Angeles, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61P 25/28 (2006.01); A61K 45/06 (2006.01); A61K 31/27 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 31/27 (2013.01); A61K 45/06 (2013.01); A61P 25/28 (2018.01);
Abstract

Disclosed is a method of treating a subject who has a neurological disease. The neurological disease may be associated with altered C9ORF72 protein activity. In one aspect, the method includes a step of administering an effective dose of a pharmaceutical composition to a subject in need thereof, thereby rescuing the defects associated with altered C9ORF72 protein activity. Also described are methods for identifying a compound for inhibiting motor neuron degeneration.


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