The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 2020
Filed:
Apr. 08, 2019
Applicant:
Array Biopharma Inc., Boulder, CO (US);
Inventors:
Shelley Allen, Boulder, CO (US);
Steven W. Andrews, Boulder, CO (US);
Kevin Ronald Condroski, Boulder, CO (US);
Julia Haas, Boulder, CO (US);
Lily Huang, Boulder, CO (US);
Yutong Jiang, Boulder, CO (US);
Timothy Kercher, Boulder, CO (US);
Jeongbeob Seo, Boulder, CO (US);
Assignee:
Array BioPharma Inc., Boulder, CO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 519/00 (2006.01); C07D 487/04 (2006.01); C07D 453/02 (2006.01); C07D 471/22 (2006.01); C07D 498/22 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 31/5377 (2013.01); C07D 453/02 (2013.01); C07D 471/22 (2013.01); C07D 487/04 (2013.01); C07D 498/22 (2013.01); C07D 519/00 (2013.01); Y02A 50/414 (2018.01);
Abstract
Compounds of Formula I: and salts thereof in which R, R, R, R, X, Y and n have the meanings given in the specification, are inhibitors of Trk kinases and are useful in the treatment of diseases which can be treated with a Trk kinase inhibitor such as pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases.