The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 2020
Filed:
Feb. 17, 2017
Applicant:
Phoenix Molecular Designs, Richmond, CA;
Inventors:
Sandra E. Dunn, Richmond, CA;
Aarthi Jayanthan, Richmond, CA;
Jaipal Reddy Nagireddy, Richmond, CA;
Subhash Annedi, Richmond, CA;
John H. Van Drie, Richmond, CA;
Timothy S. Daynard, Richmond, CA;
My-my Huynh, Richmond, CA;
Assignee:
PHOENIX MOLECULAR DESIGNS, Richmond, BC, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); A61K 31/5377 (2006.01); A61K 31/4355 (2006.01); A61K 31/496 (2006.01); A61K 31/437 (2006.01); A61K 45/06 (2006.01); C07D 471/14 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4985 (2013.01); A61K 31/437 (2013.01); A61K 31/4355 (2013.01); A61K 31/496 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07D 471/14 (2013.01);
Abstract
Described herein are carboxamide derivatives that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity. Such carboxamide derivatives form bicyclic and tricyclic ring systems and the disease or condition associated with RSK activity in a mammal is cancer.