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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10758525 B1

PDFFull Text
Date of Patent:
Sep. 01, 2020

Filed:

Oct. 02, 2018

4-methylsulfonyl-substituted piperidine urea compounds

Applicant:

Myokardia, Inc., Brisbane, CA (US);

Inventors:

Johan Oslob, Sunnyvale, CA (US);

Danielle Aubele, San Mateo, CA (US);

Jae Kim, Thousand Oaks, CA (US);

Robert McDowell, San Francisco, CA (US);

Yonghong Song, Foster City, CA (US);

Arvinder Sran, Fremont, CA (US);

Min Zhong, Palo Alto, CA (US);

Assignee:

MyoKardia, Inc., Brisbane, CA (US);

Attorneys:

Honigman LLP

Lucy X. Yang

Jonathan P. O'Brien

Primary Examiner:

Emily A Bernhardt

Int. Cl.
CPC ...
A61P 9/10 (2006.01); A61K 31/454 (2006.01); A61K 31/501 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01); A61K 31/4545 (2006.01); C07D 401/14 (2006.01); A61K 31/496 (2006.01); A61K 31/506 (2006.01); A61K 45/06 (2006.01); C07D 401/12 (2006.01); C07D 405/14 (2006.01); C07D 471/04 (2006.01); C07D 411/14 (2006.01); C07D 409/02 (2006.01); C07D 407/14 (2006.01); C07D 407/02 (2006.01); C07D 401/02 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4545 (2013.01); A61K 31/454 (2013.01); A61K 31/496 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 45/06 (2013.01); C07D 401/02 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 407/02 (2013.01); C07D 407/14 (2013.01); C07D 409/02 (2013.01); C07D 411/14 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention provides novel 4-methylsulphone-substituted piperidine urea compounds that are useful for the treatment of dilated cardiomyopathy (DCM) and conditions associated with left and/or right ventricular systolic dysfunction or systolic reserve. The synthesis and characterization of the compounds is described, as well as methods for treating DCM and other forms of heart disease.

Find Patent Forward Citations

Oslob, Johan. (2020). 4-methylsulfonyl-substituted piperidine urea compounds (U.S. Patent No. 10758525). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10758525

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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