The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 2020
Filed:
Aug. 07, 2018
Applicant:
Bioventures, Llc, Little Rock, AR (US);
Inventors:
Guangrong Zheng, Little Rock, AR (US);
Daohong Zhou, Little Rock, AR (US);
Xingui Liu, Little Rock, AR (US);
Yingying Wang, Little Rock, AR (US);
Jianhui Chang, Little Rock, AR (US);
Wei Feng, Little Rock, AR (US);
Lijian Shao, Little Rock, AR (US);
Yi Luo, Little Rock, AR (US);
Assignee:
BioVentures, LLC, Little Rock, AR (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/45 (2006.01); A61K 31/55 (2006.01); A61K 31/4015 (2006.01); A61K 31/5377 (2006.01); A61K 31/4412 (2006.01); A61K 31/443 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); A61K 31/4545 (2006.01); A61K 31/635 (2006.01); C07D 223/10 (2006.01); C07D 401/06 (2006.01); C07D 405/06 (2006.01); C07D 207/38 (2006.01); C07D 211/88 (2006.01); A23L 33/10 (2016.01); C07D 211/76 (2006.01); C07D 211/96 (2006.01);
U.S. Cl.
CPC ...
A61K 31/45 (2013.01); A23L 33/10 (2016.08); A61K 31/4015 (2013.01); A61K 31/443 (2013.01); A61K 31/444 (2013.01); A61K 31/4412 (2013.01); A61K 31/4439 (2013.01); A61K 31/4545 (2013.01); A61K 31/5377 (2013.01); A61K 31/55 (2013.01); A61K 31/635 (2013.01); C07D 207/38 (2013.01); C07D 211/76 (2013.01); C07D 211/88 (2013.01); C07D 211/96 (2013.01); C07D 223/10 (2013.01); C07D 401/06 (2013.01); C07D 405/06 (2013.01); A23V 2002/00 (2013.01);
Abstract
The present disclosure provides compositions and methods for selectively killing senescent cells, wherein the composition comprises piperlongumine (PL) or derivative thereof. The selective killing of senescent cells may delay aging and/or treat age-related disorders.