The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2020
Filed:
Aug. 29, 2014
Applicant:
D.e. Shaw Research, Llc, New York, NY (US);
Inventors:
Morten Østergaard Jensen, New York, NY (US);
David Wayne Borhani, Hartsdale, NY (US);
Vishwanath Jogini, Hyderabad, IN;
Assignee:
D.E. SHAW RESEARCH, LLC, New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/68 (2006.01); C12Q 1/42 (2006.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6872 (2013.01); C12Q 1/42 (2013.01); G01N 33/48721 (2013.01); G01N 33/48728 (2013.01); G01N 33/6842 (2013.01); G01N 2333/916 (2013.01); G01N 2500/00 (2013.01); G01N 2500/04 (2013.01);
Abstract
In one aspect, the invention relates to a method for identifying a compound which modulates the activity of a voltage-gated protein. In certain embodiments, the voltage gate protein is a voltage-gated ion channel. In certain embodiments, the voltage-gated protein is a voltage sensitive phosphatase. In certain embodiments, the voltage-gated protein used in conjunction with the methods of the invention is modified to altered permeability or voltage sensitivity.