The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2020

Filed:

Jul. 27, 2016
Applicant:

Thermo Finnigan Llc, San Jose, CA (US);

Inventors:

Joseph Herman, West Chester, PA (US);

Sarah J. Fair, Manchaug, MA (US);

Dayana Argoti, Charlestown, MA (US);

Assignee:

Thermo Finnigan LLC, San Jose, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 30/00 (2006.01); G01N 30/46 (2006.01); G01N 30/02 (2006.01); G01N 30/08 (2006.01); G01N 30/14 (2006.01); G01N 30/62 (2006.01);
U.S. Cl.
CPC ...
G01N 30/462 (2013.01); G01N 30/02 (2013.01); G01N 30/08 (2013.01); G01N 30/14 (2013.01); G01N 30/468 (2013.01); G01N 2030/027 (2013.01); G01N 2030/143 (2013.01); G01N 2030/628 (2013.01);
Abstract

A method for analyzing and quantifying a panel of drugs in a clinical sample comprises: trapping a first portion of drug parent compounds and their metabolites on a first chromatographic column; trapping a second portion of the drug parent compounds and their metabolites on a second chromatographic column; separately eluting the first and second portions of the drug parent compounds and their metabolites from the first and second chromatographic columns; detecting concentrations of each of the drug parent compounds and metabolites eluted from each of the first and second chromatographic columns with a detector; and summing the detected concentration of each drug parent compound together with the detected concentrations of all of its respective analytes so as to derive a respective total concentration of each drug in the sample.


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