The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2020
Filed:
May. 20, 2019
Applicant:
Merus N.v., Utrecht, NL;
Inventors:
Cornelis Adriaan De Kruif, Utrecht, NL;
Linda Johanna Aleida Hendriks, Utrecht, NL;
Ton Logtenberg, Utrecht, NL;
Assignee:
Merus N.V., Utrecht, NL;
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/00 (2006.01); C07K 16/12 (2006.01); C07K 16/26 (2006.01); C07K 16/36 (2006.01); C07K 16/46 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 39/40 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12P 21/005 (2013.01); A61K 39/395 (2013.01); A61K 39/3955 (2013.01); A61K 39/40 (2013.01); C07K 16/12 (2013.01); C07K 16/1278 (2013.01); C07K 16/1282 (2013.01); C07K 16/18 (2013.01); C07K 16/26 (2013.01); C07K 16/28 (2013.01); C07K 16/283 (2013.01); C07K 16/2809 (2013.01); C07K 16/2866 (2013.01); C07K 16/2896 (2013.01); C07K 16/36 (2013.01); C07K 16/468 (2013.01); A61K 2039/507 (2013.01); C07K 2317/14 (2013.01); C07K 2317/31 (2013.01); C07K 2317/526 (2013.01); C07K 2317/56 (2013.01); C07K 2317/94 (2013.01);
Abstract
The invention provides means and methods for producing one or more Ig-like molecules in a single host cell. Novel CH3 mutations enabling the production of monospecific and/or bispecific Ig-like molecules of interest are also provided.