The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2020
Filed:
Apr. 15, 2019
Applicant:
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Inventors:
Scott M. Walsh, Sewickley, PA (US);
Daniel B. Dix, Lagrangeville, NY (US);
Assignee:
REGENERON PHARMACEUTICALS, INC., Tarrytown, NY (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); A61K 39/395 (2006.01); A61K 47/22 (2006.01); A61K 47/26 (2006.01); A61M 5/32 (2006.01); A61M 5/315 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 39/3955 (2013.01); A61K 39/39591 (2013.01); A61K 47/22 (2013.01); A61K 47/26 (2013.01); A61M 5/31513 (2013.01); A61M 5/3202 (2013.01); C07K 2317/565 (2013.01); C07K 2317/94 (2013.01);
Abstract
The present invention provides pharmaceutical formulations comprising a human antibody that specifically binds to human proprotein convertase subtilisin/kexin type 9 (PCSK9). The formulations may contain, in addition to an anti-PCSK9 antibody, at least one amino acid, at least one sugar, or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months.