The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2020
Filed:
Dec. 30, 2017
Development Center for Biotechnology, New Taipei, TW;
Yu-Chen Yang, New Taipei, TW;
Li-Yu Chen, Macau, MO;
Chia-Hua Li, New Taipei, TW;
Pei-Han Tai, New Taipei, TW;
Hong-Kai Chen, New Taipei, TW;
Ying-Yung Lok, New Taipei, TW;
Chih-Yung Hu, New Taipei, TW;
Chien-Tsun Kuan, New Taipei, TW;
Chung-Hsiun Wu, New Taipei, TW;
DEVELOPMENT CENTER FOR BIOTECHNOLOGY, Taipei, TW;
Abstract
An anti-human T-cell immunoglobulin domain and mucin domain 3 (TIM-3) antibody, can bind the peptides, comprising the amino-acid sequence RKGDVSL (SEQ ID NO: 9) and/or EKFNLKL (SEQ ID NO: 10) of human TIM-3 protein. The antibody can regulate immune cell activity. The antibody or binding fragment thereof is useful in diagnosis, prognosis, and treatment of cancers that have been reported to express cell-surface TIM-3 such as lung, liver, esophageal cancer and solid tumors.