The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2020
Filed:
Jul. 27, 2017
Applicant:
Guangzhou Innocare Pharma Tech Co., Ltd., Guangzhou, CN;
Inventors:
Assignee:
Guangzhou Innocare Pharma Tech Co., Ltd., Guangzhou, Guangdong, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 471/04 (2006.01); A61P 35/04 (2006.01); A61P 35/00 (2006.01); A61K 31/525 (2006.01); A61K 31/437 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/437 (2013.01); A61K 31/525 (2013.01); A61P 35/00 (2018.01); A61P 35/04 (2018.01); C07D 471/04 (2013.01);
Abstract
The present invention relates to a heterocyclic compound, a pharmaceutical composition containing the same, a preparation method thereof, and a use thereof as a fibroblast growth factor receptor (FGFR) inhibitor. The compound is a heterocyclic compound as shown in Formula I, or a pharmaceutically acceptable salt, a prodrug, a solvate, a polymorph, an isomer, or a stable isotopic derivative thereof. The present invention further relates to a method of treating or preventing a FGFR-mediated disease, such as cancer, using the compound.