The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2020

Filed:

Mar. 15, 2018
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Jing Su, Scotch Plains, NJ (US);

Lihu Yang, Edison, NJ (US);

Takao Suzuki, Shanghai, CN;

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); C07D 263/22 (2006.01); C07D 413/10 (2006.01); C07D 417/14 (2006.01); A61P 31/06 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); A61K 9/0014 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61P 31/06 (2018.01); C07D 263/22 (2013.01); C07D 413/10 (2013.01); C07D 417/14 (2013.01);
Abstract

The present invention relates to oxazolidinone Compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein A, E, and R1 are as defined herein. The present invention also relates to compositions which comprise at least one oxazolidinone compound of the invention. The invention also provides methods for inhibiting growth of mycobacterial cells as well as a method of treating mycobacterial infections by Mycobacterium tuberculosis comprising administering a therapeutically effective amount of an oxazolidinone of the invention and/or a pharmaceutically acceptable salt thereof, or a composition comprising such compound and/or salt.


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