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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10752615 B1

PDFFull Text
Expired
Date of Patent:
Aug. 25, 2020

Filed:

Aug. 16, 2017

Spirocyclic containing compounds and pharmaceutical uses thereof

Applicant:

Gb005, Inc., San Diego, CA (US);

Inventors:

Alain Laurent, Lachine, CA;

Stephen J. Morris, Beaconsfield, CA;

Assignee:

GB005, Inc., San Diego, CA (US);

Attorney:

Seed IP Law Group LLP

Primary Examiner:

Laura L Stockton

Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 407/14 (2006.01); A61P 25/28 (2006.01); A61K 31/4184 (2006.01); A61K 31/422 (2006.01); A61K 31/427 (2006.01); A61K 31/437 (2006.01); A61K 31/4439 (2006.01); A61K 31/497 (2006.01); A61K 31/506 (2006.01); A61K 45/06 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 409/14 (2013.01); A61K 31/4184 (2013.01); A61K 31/422 (2013.01); A61K 31/427 (2013.01); A61K 31/437 (2013.01); A61K 31/4439 (2013.01); A61K 31/497 (2013.01); A61K 31/506 (2013.01); A61K 45/06 (2013.01); A61P 25/28 (2018.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention relates to a novel family of covalent kinases inhibitors, compounds of this class have been found to have inhibitory activity against members of the TEC kinase family, particularly ITK and/or TXK, BTK, TEC and/or combinations thereof. The present invention is directed to a compound of Formula I or pharmaceutically acceptable salt, solvate, solvates of salt, stereoisomer, tautomer, isotope, prodrug, complex or biologically active metabolite thereof, for use in therapy.

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Laurent, Alain. (2020). Spirocyclic containing compounds and pharmaceutical uses thereof (U.S. Patent No. 10752615). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10752615

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