The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2020

Filed:

Dec. 18, 2015
Applicants:

The Broad Institute, Inc., Cambridge, MA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Edward Holson, Newton, MA (US);

Florence Fevrier, Ashland, MA (US);

Michel Weiwer, Cambridge, MA (US);

Edward Scolnick, Wayland, MA (US);

Michelle Palmer, Harvard, MA (US);

Michael C. Lewis, Dedham, MA (US);

Jennifer Q. Pan, Acton, MA (US);

Yan-Ling Zhang, Lexington, MA (US);

Qihong Xu, Newton, MA (US);

Assignees:

The Broad Institute, Inc., Cambridge, MA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/26 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 401/12 (2006.01); C07D 413/12 (2006.01); C07D 471/04 (2006.01); C07D 471/10 (2006.01); C07D 211/62 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
C07D 211/26 (2013.01); A61P 25/00 (2018.01); C07D 211/62 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 413/12 (2013.01); C07D 471/04 (2013.01); C07D 471/10 (2013.01);
Abstract

The present invention relates to novel dopamine D2 receptor ligands. The invention further relates to functionally-biased dopamine D2 receptor ligands and the use of these compounds for treating or preventing central nervous system and systemic disorders associated with dysregulation of dopaminergic activity.


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