The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2020
Filed:
Aug. 06, 2018
Applicant:
Council of Scientific & Industrial Research, New Delhi, IN;
Inventors:
Chandrasekhar Srivari, Telangana, IN;
Prathama Satyendra Mainkar, Telangana, IN;
Srinu Paladugu, Telangana, IN;
Pavan Kumar Togapur, Telangana, IN;
Assignee:
Council of Scientific & Industrial Research, New Delhi, IN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/04 (2006.01);
U.S. Cl.
CPC ...
C07D 209/04 (2013.01);
Abstract
The present invention relates to a process for the preparation of (1-alkylindol-3-ylmethyl) benzoic acid derivatives, in particular Zafirlukast and analogs thereof. Further, this process is based on protection group free and C—H bond activation strategy involving all step catalytic transformation sequence and comprises the following steps: Sonogashira coupling, indole formation by SpC—H activation, reductive hydrogenation and amidation.