The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2020
Filed:
Sep. 19, 2014
Applicant:
Novavax, Inc., Gaithersburg, MD (US);
Inventors:
Gale Smith, Gaithersburg, MD (US);
Ye Liu, Gaithersburg, MD (US);
Michael Massare, Gaithersburg, MD (US);
Assignee:
Novavax, Inc., Gaithersburg, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); A61K 39/145 (2006.01); A61K 9/00 (2006.01); A61K 9/127 (2006.01); A61K 9/51 (2006.01); A61K 39/215 (2006.01); A61K 39/12 (2006.01); A61K 39/42 (2006.01); C07K 14/005 (2006.01); C07K 16/10 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/215 (2013.01); A61K 39/12 (2013.01); A61K 39/42 (2013.01); C07K 14/005 (2013.01); C07K 16/10 (2013.01); C12N 7/00 (2013.01); A61K 2039/505 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/552 (2013.01); A61K 2039/575 (2013.01); C07K 2317/92 (2013.01); C12N 2770/20022 (2013.01); C12N 2770/20034 (2013.01); C12N 2770/20071 (2013.01);
Abstract
Disclosed herein are nanoparticles containing MERS virus proteins in polymer structures, and compositions containing the nanoparticles formulated for administration as immunogenic compositions. Also provided herein are vector constructs encoding the proteins, and host cells containing the vector constructs. The disclosure also includes methods of making the nanoparticles and administering them to vertebrates, including methods of inducing immune responses to MERS that reduce or prevent infection by the virus.