The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2020

Filed:

Nov. 01, 2017
Applicant:

Pfizer Inc., New York, NY (US);

Inventors:

Annaliesa Sybil Anderson, Upper Saddle River, NJ (US);

Leena Shriram Bagle, Edgewater, NJ (US);

Amardeep Singh Bhupender Bhalla, Montvale, NJ (US);

Miguel Angel Garcia, Midland Park, NJ (US);

Lei Hu, New City, NY (US);

Lakshmi Khandke, Nanuet, NY (US);

Avvari Krishna Prasad, Chapel Hill, NC (US);

Cindy Xudong Yang, Tappan, NY (US);

Assignee:

Pfizer Inc., New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/02 (2006.01); A61K 39/09 (2006.01); A61K 39/39 (2006.01);
U.S. Cl.
CPC ...
A61K 39/092 (2013.01); A61K 39/39 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/6037 (2013.01); A61K 2039/6068 (2013.01); A61K 2039/70 (2013.01);
Abstract

The invention relates to immunogenic compositions comprising a capsular polysaccharide (CP) from, commonly referred to as group B streptococcus (GBS), conjugated to a carrier protein, and optionally including an aluminum-based adjuvant. The invention further relates to methods for inducing an immune response in subjects against GBS and/or for reducing or preventing invasive GBS disease in subjects using the compositions disclosed herein. The resulting antibodies can be used to treat or prevent GBS infection via passive immunotherapy.


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