The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2020
Filed:
Oct. 09, 2017
Applicant:
Loyola University of Chicago, Maywood, IL (US);
Inventors:
Liang Qiao, Woodridge, IL (US);
Zhenyu Zhong, San Diego, CA (US);
Yougang Zhai, Countryside, IL (US);
Assignee:
Loyola University Chicago, Maywood, IL (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); A61K 39/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 39/12 (2013.01); A61P 35/00 (2018.01); A61K 2039/5256 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/585 (2013.01); A61K 2039/828 (2018.08); A61K 2039/836 (2018.08); C12N 2710/20023 (2013.01); C12N 2710/20034 (2013.01);
Abstract
Compositions and treatments for inducing tumor regression by activating inflammasomes in tumor cells and tumor-associated cells. A tumor in a subject is treated by administering a composition to the subject that activates inflammasomes in cells of the tumor and thereby causes tumor cell pyroptosis and tumor regression.