The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2020
Filed:
Jan. 23, 2017
Applicant:
Cerion, Llc, Rochester, NY (US);
Inventors:
Bradford Michael Stadler, Brighton, NY (US);
David Wallace Sandford, Rochester, NY (US);
Assignee:
Cerion LLC, Rochester, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/24 (2019.01); C01F 17/206 (2020.01); B82Y 30/00 (2011.01); A61K 9/51 (2006.01); A61K 47/12 (2006.01); A61K 47/18 (2017.01); A61K 9/10 (2006.01); A61K 47/02 (2006.01);
U.S. Cl.
CPC ...
A61K 33/24 (2013.01); A61K 9/10 (2013.01); A61K 9/5123 (2013.01); A61K 9/5192 (2013.01); A61K 47/02 (2013.01); A61K 47/12 (2013.01); A61K 47/18 (2013.01); A61K 47/183 (2013.01); B82Y 30/00 (2013.01); C01F 17/206 (2020.01); C01P 2002/30 (2013.01); C01P 2002/76 (2013.01); C01P 2004/64 (2013.01);
Abstract
A process for making cerium-containing nanoparticles with biocompatible stabilizers is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid, a stabilizer (chelator) selected from the group consisting of nitrilotriacetic acid, ethylene glycol tetraacetic acid and diethylenetriaminepentaacetic acid, and an oxidant, is provided, followed by a heating step to effectively form the nanoparticles. These biocompatible nanoparticles can be used to treat oxidative stress related diseases and events, such as ischemic stroke.