The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2020

Filed:

Oct. 17, 2017
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Dan Stoianovici, Reisterstown, MD (US);

Doyoung Chang, Rosedale, MD (US);

Misop Han, West Friendship, MD (US);

Assignee:

The Johna Hopkins University, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 10/02 (2006.01); A61B 34/10 (2016.01); G16H 40/63 (2018.01); G16H 50/50 (2018.01);
U.S. Cl.
CPC ...
A61B 10/0241 (2013.01); A61B 5/4381 (2013.01); A61B 5/7275 (2013.01); A61B 34/10 (2016.02); G16H 40/63 (2018.01); G16H 50/50 (2018.01); A61B 5/4887 (2013.01); A61B 2034/105 (2016.02); A61B 2034/107 (2016.02); A61B 2576/02 (2013.01);
Abstract

The present invention is directed to a method for calculating tumor detection probability of a biopsy plan and for generating a 3D biopsy plan that maximizes tumor detection probability. A capsule shaped volume is modeled to represent the volume that a biopsy core may sample. An optimization method is used to generate a 3D biopsy plan that maximizes probability of tumor detection for predefined biopsy core numbers and length. Risk of detecting insignificant tumors, also determined by size, and probability of a false negative result is automatically calculated. The present invention also includes a method to determine number and length of biopsy cores required for individual patients determined by the balance of the insignificant/significant probability of detection, prostate size and shape, based upon the previously explained 3D biopsy plan generation method.


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