The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Feb. 24, 2014
Applicant:

Siemens Healthcare Gmbh, Erlangen, DE;

Inventors:

Chloe Audigier, Valbonnes, FR;

Tommaso Mansi, Plainsboro, NJ (US);

Viorel Mihalef, North Brunswick, NJ (US);

Ali Kamen, Skillman, NJ (US);

Dorin Comaniciu, Princeton Junction, NJ (US);

Puneet Sharma, Monmouth Junction, NJ (US);

Saikiran Rapaka, Ewing, NJ (US);

Assignee:

Siemens Healthcare GmbH, Erlangen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); G09B 5/02 (2006.01); A61B 34/10 (2016.01); A61B 6/00 (2006.01); A61B 6/03 (2006.01); G16H 50/50 (2018.01); G09B 23/30 (2006.01); A61B 18/00 (2006.01);
U.S. Cl.
CPC ...
G09B 5/02 (2013.01); A61B 6/032 (2013.01); A61B 6/50 (2013.01); A61B 6/5217 (2013.01); A61B 34/10 (2016.02); G09B 23/30 (2013.01); G09B 23/303 (2013.01); G16H 50/50 (2018.01); A61B 2018/00404 (2013.01); A61B 2018/00529 (2013.01); A61B 2034/104 (2016.02); A61B 2034/105 (2016.02); A61B 2034/107 (2016.02);
Abstract

A method and system for interactive patient-specific simulation of liver tumor ablation is disclosed. A patient-specific anatomical model of the liver and circulatory system of the liver is estimated from 3D medical image data of a patient. A computational domain is generated from the patient-specific anatomical model of the liver. Blood flow in the liver and the circulatory system of the liver is simulated based on the patient-specific anatomical model. Heat diffusion due to ablation is simulated based on a virtual ablation probe position and the simulated blood flow in the liver and the circulatory system of the liver by solving a bio-heat equation for each node on the level-set representation using a Lattice-Boltzmann method (LBM) implementation. Cellular necrosis in the liver is computed based on the simulated heat diffusion. Visualizations of a computed necrosis region and temperature maps of the liver are generated. A user input is interactively received to modify the position of the virtual ablation probe, the heat diffusion and cellular necrosis is re-simulated based on the user input, and the visualizations of the computed necrosis region and the temperature maps are updated.


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