The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Jun. 02, 2015
Applicants:

Valley Health System, Paramus, NJ (US);

The Wistar Institute, Philadelphia, PA (US);

Inventors:

Kiranmai Gumireddy, Bryn Mawr, PA (US);

Qihong Huang, Wynnewood, PA (US);

Louise C. Showe, Media, PA (US);

Ganepola A Ganepola, Hillsdale, NJ (US);

Assignees:

Valley Health System, Paramus, NJ (US);

The Wistar Institute of Anatomy and Biology, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); G16H 50/30 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/158 (2013.01); G16H 50/30 (2018.01);
Abstract

The present invention relates to methods and systems for high risk screening, diagnosis, prognosis, and surveillance of lung cancer. Accordingly, in one aspect, the invention provides a method for diagnosing or evaluating whether a subject has, or is at risk of having, lung cancer such as NSCLS. The method comprises obtaining a first expression level of the AKAP4 gene of a population of cells from the blood of a test subject; and comparing the first expression level with a first predetermined reference value. A difference between the first expression level and first predetermined reference value correlates with a diagnosis or evaluation of a lung cancer.


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