The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Oct. 01, 2015
Applicant:

Centre for Addiction and Mental Health, Toronto, CA;

Inventors:

Jeffrey Meyer, Toronto, CA;

Ken Evans, Toronto, CA;

Jian Chen, Toronto, CA;

Suzanne Ackloo, Toronto, CA;

Moyez Dharsee, Toronto, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); G01N 33/567 (2006.01); C12Q 1/26 (2006.01); C40B 40/10 (2006.01); C12N 9/06 (2006.01); C07K 7/08 (2006.01); C07K 7/06 (2006.01); A61B 5/11 (2006.01); A61B 5/145 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/26 (2013.01); A61B 5/1127 (2013.01); A61B 5/145 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C12N 9/0022 (2013.01); C12Q 1/68 (2013.01); C12Y 104/03004 (2013.01); C40B 40/10 (2013.01); G01N 33/5008 (2013.01); G01N 2333/90638 (2013.01); G01N 2560/00 (2013.01); G01N 2800/304 (2013.01);
Abstract

Disclosed is a method for diagnosing a mood disorder or susceptibility to a mood disorder, including depressive disorders and bipolar disorder, from a biological sample taken from a subject. The method includes detecting markers of monoamine oxidase-A (MAO-A) in the biological sample; determining MAO-A concentration from the markers; and correlating the MAO-A concentration in the biological sample to a control group which does not have a mood disorder in order to diagnose or determine susceptibility to the mood disorder in the subject. Also disclosed is a method of detecting peripheral markers of MAO-A for the diagnosis of a mood disorder or susceptibility to a mood disorder. Also provided are polypeptide markers.


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