The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Jul. 14, 2017
Applicant:

The Research Foundation for the State University of New York, Albany, NY (US);

Inventors:

Christopher T. Nomura, Syracuse, NY (US);

Ryan C. Tappel, Syracuse, NY (US);

Qin Wang, Syracuse, NY (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 7/62 (2006.01); C12N 9/88 (2006.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
C12P 7/62 (2013.01); C12N 9/1029 (2013.01); C12N 9/88 (2013.01); C12P 7/625 (2013.01); C12Y 203/01 (2013.01); C12Y 402/01017 (2013.01); C12Y 402/01055 (2013.01);
Abstract

Methods and systems for producing prescribed unit size poly(3-hydroxyalkanoate) (PHA) polymers and copolymers are provided. The methods and systems can employ recombinant bacteria that are not native producers of PHA or lack enzymes to degrade PHA once synthesized, metabolize short to long chain fatty acids without induction, and express an (R)-specific enoyl-CoA hydratase and a PHA synthase, the (R)-specific enoyl-CoA hydratase and PHA synthase having wide substrate specificities. The recombinant bacteria are fed at least one fatty acid substrate that is equal in carbon length to the prescribed or desired unit size of the PHA polymer to be produced. The prescribed unit size PHA that is produced is then isolated and/or purified.


Find Patent Forward Citations

Loading…