The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Aug. 28, 2015
Applicant:

Ethris Gmbh, Martinsried, DE;

Inventors:

Carsten Rudolph, Munich, DE;

Michael Kormann, Erding, DE;

Assignee:

ETHRIS GMBH, Planegg, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/63 (2006.01); C12N 15/11 (2006.01); A61K 48/00 (2006.01); C12N 15/67 (2006.01); A61L 27/22 (2006.01); A61K 38/18 (2006.01); C07K 14/505 (2006.01); C07K 14/785 (2006.01); A01K 67/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/11 (2013.01); A61K 38/1816 (2013.01); A61K 48/0066 (2013.01); A61L 27/227 (2013.01); C07K 14/505 (2013.01); C07K 14/785 (2013.01); C12N 15/67 (2013.01); A61K 48/00 (2013.01); C12N 2310/334 (2013.01); C12N 2310/335 (2013.01); C12N 2320/30 (2013.01); C12N 2320/50 (2013.01);
Abstract

The invention relates to a polyribonucleotide with a sequence that codes a protein or protein fragment, wherein the polyribonucleotide comprises a combination of unmodified and modified nucleotides, wherein 5 to 50% of the uridine nucleotides and 5 to 50% of the cytidin nucleotides are modified uridine nucleotides or modified cytidin nucleotides.


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