The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 2020
Filed:
Feb. 14, 2019
Applicant:
Italfarmaco S.p.a., Milan, IT;
Inventors:
Assignee:
ITALFARMACO S.P.A., Milan, IT;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C40B 40/08 (2006.01); C12N 15/10 (2006.01); C40B 40/10 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1082 (2013.01); C07K 16/00 (2013.01); C40B 40/08 (2013.01); C40B 40/10 (2013.01); C07K 2317/526 (2013.01);
Abstract
The present invention provides for a library of vectors comprising human HC-CDR3 regions of varying length, wherein the diversity of said library is focused on the HC-CDR3 region only and diversity has been optimized such that redundancy is reduced for short HC-CDR3 loops and coverage of HC-CDR3 region variants for longer loop lengths has been increased. The library of the present invention is displayed on phage for selection against target antigens.