The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Mar. 05, 2015
Applicants:

Salk Institute for Biological Studies, La Jolla, CA (US);

The Regents of the University of California, Oakland, CA (US);

Inventors:

Joseph Noel, La Jolla, CA (US);

Kate Woods, La Jolla, CA (US);

Marianne Bowman, La Jolla, CA (US);

Gordon Louie, La Jolla, CA (US);

Nancy Anderson Da Silva, Oakland, CA (US);

Javier Pascual Cardenas, Oakland, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/52 (2006.01); C12N 15/09 (2006.01); C12N 9/10 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1029 (2013.01); C12N 15/52 (2013.01); C12Y 203/01 (2013.01);
Abstract

The present invention relates to methods for producing polyketide synthase variants, and for altering the activity and/or substrate specificity of putative native and variant polyketide synthases. The present invention further relates to compositions comprising said polyketide synthase variants, compounds prepared using said polyketide synthase variants, and uses of said polyketide synthase variants. In one embodiment, said polyketide synthase variant is 2-pyrone synthase.


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