The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 2020
Filed:
Nov. 08, 2019
Applicant:
Precision Biosciences, Inc., Durham, NC (US);
Inventors:
Joann Hux, Scotland Neck, NC (US);
Aaron Martin, Carrboro, NC (US);
Derek Jantz, Durham, NC (US);
Clayton Beard, Durham, NC (US);
Assignee:
Precision BioSciences, Inc., Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); C07K 14/725 (2006.01); C07K 14/74 (2006.01); C07K 16/28 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0636 (2013.01); C07K 14/7051 (2013.01); C07K 14/70539 (2013.01); C07K 16/2803 (2013.01); C12N 15/1138 (2013.01); C07K 2319/00 (2013.01); C12N 2310/14 (2013.01); C12N 2310/531 (2013.01);
Abstract
The present disclosure provides nucleic acid molecules encoding an engineered antigen receptor, such as a chimeric antigen receptor or exogenous T cell receptor, and an inhibitory nucleic acid molecule, such as an RNA interference molecule. The present disclosure further relates to nucleic acids, DNA constructs, vectors, pharmaceutical compositions, genetically-modified cells, and methods of treatment that utilize the nucleic acid molecules of the invention.