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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10745663 B1

PDFFull Text
Date of Patent:
Aug. 18, 2020

Filed:

Jul. 07, 2016

Methods for modulating production profiles of recombinant proteins

Applicant:

Ares Trading S.a., Aubonne, CH;

Inventors:

Anais Muhr, Champigneulles, FR;

David Bruhlmann, Lausanne, CH;

Martin Jordan, Ecublens, CH;

Herve Broly, Chatel-St-Denis, CH;

Matthieu Stettler, Sierre, CH;

Assignee:

ARES TRADING S.A., Aubonne, CH;

Attorney:

Saliwanchik, LLoyd & Eisenschenk

Primary Examiner:

Paul J Holland

Int. Cl.
CPC ...
C12N 5/00 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0018 (2013.01); C07K 16/18 (2013.01); C07K 16/28 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C12N 2501/999 (2013.01); C12N 2511/00 (2013.01);
Abstract

The invention is in the field of cell culture. Particularly the invention relates to methods of culturing a host cell expressing a recombinant protein in a cell culture medium comprising an effective amount of 4,4'diisothiocyanostilbene-2,2′-disulfonic acid (DIDS) or supplemented with an effective amount of DIDS, whereby production of said protein is increased relative to cells grown without DIDS.

Find Patent Forward Citations

Muhr, Anais. (2020). Methods for modulating production profiles of recombinant proteins (U.S. Patent No. 10745663). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10745663

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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