The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Feb. 19, 2019
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Ehud Y. Isacoff, Berkeley, CA (US);

Michael H. Berry, Berkeley, CA (US);

Amy Holt, Berkeley, CA (US);

Meike Visel, El Cerrito, CA (US);

Autoosa Salari, Berkeley, CA (US);

John G. Flannery, Berkeley, CA (US);

Benjamin M. Gaub, Berkeley, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07K 14/47 (2006.01); C12N 15/864 (2006.01); C12N 5/10 (2006.01); A61P 27/04 (2006.01); C12N 15/85 (2006.01); A61K 9/00 (2006.01); A61K 9/51 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/47 (2013.01); A61K 9/0019 (2013.01); A61K 9/0048 (2013.01); A61K 9/5138 (2013.01); A61K 9/5153 (2013.01); A61K 48/0058 (2013.01); A61K 48/0075 (2013.01); A61K 48/0083 (2013.01); A61P 27/04 (2018.01); C12N 15/85 (2013.01); A61K 38/00 (2013.01); C12N 2750/14143 (2013.01);
Abstract

The present disclosure provides a method of restoring or enhancing visual function in an individual, the method comprising administering to the individual a nucleic acid comprising a nucleotide sequence encoding one or more of a medium wavelength cone opsin (MW-opsin), a long wavelength cone opsin (LW-opsin), and a short wavelength cone opsin (SW-opsin). One or more of the MW-opsin, LW-opsin, and SW-opsin is expressed in a retinal cell in the individual, thereby restoring or enhancing visual function.


Find Patent Forward Citations

Loading…