The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Dec. 05, 2016
Applicants:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Idenix Pharmaceuticals Llc, Cambridge, MA (US);

Inventors:

Izzat Tiedje Raheem, Doylestown, PA (US);

Timothy J. Hartingh, Richlandtown, PA (US);

John Schreier, Harleysville, PA (US);

Jean-Laurent Paparin, Montpellier, FR;

Assignees:

IDENIX PHARMACEUTICALS LLC, Cambridge, MA (US);

MERCK SHARP & DOHME CORP., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/675 (2006.01); C07F 9/6561 (2006.01); A61P 31/18 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07F 9/65616 (2013.01); A61K 31/675 (2013.01); A61K 45/06 (2013.01); A61P 31/18 (2018.01);
Abstract

Compounds of Formula I and pharmaceutically acceptable salts and co-crystals thereof are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.


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