The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Sep. 11, 2019
Applicant:

Euticals Spa, Milan, IT;

Inventors:

Paride Grisenti, Milan, IT;

Maria Argese, Sedriano, IT;

Daniele Pengo, Paderno Dungnano, IT;

Maria Donata Grilli, Cusano Milanino, IT;

Emanuela Fumagalli, Lainate, IT;

Giuseppe Motta, Rescaldina, IT;

Assignee:

AMRI ITALY S.R.L., Milan, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/22 (2006.01); A61K 9/20 (2006.01); A61K 9/28 (2006.01); A61K 31/437 (2006.01);
U.S. Cl.
CPC ...
C07D 498/22 (2013.01); A61K 9/2095 (2013.01); A61K 9/28 (2013.01); A61K 9/2893 (2013.01); A61K 31/437 (2013.01);
Abstract

A Rifaximin polymorphic mixture of α/β form in a relative ratio of 85/15±3 and a process for its preparation. The polymorphic mixture of Rifaximin is for use as a medicament, in particular in the treatment of traveler's diarrhea and hepatic encephalopathy. A pharmaceutical composition comprises the polymorphic mixture of Rifaximin as active ingredient, in particular, a solid formulation, more in particular, a film coated tablet. A polymorphic form of crude wet rifaximin and of purified wet rifaximin their use are used as intermediates in a process for the preparation of Rifaximin polymorphic mixture of α/β form in a relative ratio of 85/15±3.


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