The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 2020
Filed:
May. 22, 2018
Applicant:
Theravance Biopharma R&d Ip, Llc, South San Francisco, CA (US);
Inventors:
Daniel D. Long, San Francisco, CA (US);
Donna A. A. Wilton, San Francisco, CA (US);
Mandy M. Loo, San Jose, CA (US);
Ryan Hudson, San Jose, CA (US);
Patrick J. Brassil, Redwood City, CA (US);
Assignee:
Theravance Biopharma R&D IP, LLC, South San Francisco, CA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61P 29/00 (2006.01); C07H 17/02 (2006.01); C07H 15/26 (2006.01); C07H 1/00 (2006.01); C07H 13/12 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 29/00 (2018.01); C07H 1/00 (2013.01); C07H 13/12 (2013.01); C07H 15/26 (2013.01); C07H 17/02 (2013.01);
Abstract
The invention relates to glucuronide prodrug compounds of Janus kinase (JAK) inhibitors having formula I: where W, Rand Aare as defined. The invention also relates to pharmaceutical compositions comprising such compounds; methods of using such compounds to treat gastrointestinal inflammatory diseases; and processes and intermediates for preparing such compounds.