IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10745395 B1

PDFFull Text
Date of Patent:
Aug. 18, 2020

Filed:

Aug. 26, 2015

Compounds for their use as drugs for the treatment and/or the prevention of infection(s) caused by biofilm-forming bacteria

Applicants:

Centre National DE LA Recherche Scientifique, Paris, FR;

Universite D'orleans, Orleans Cede, FR;

Jagiellonian University, Cracow, PL;

Inventors:

Olivier Martin, Saint-Hilaire-Saint-Mesmin, FR;

Estelle Gallienne-Boivineau, Lingny le Ribault, FR;

Cyril Nicolas, Nouan-le-fuzlier, FR;

Piotr B. Heczko, Cracow, PL;

Grazyna Stochel, Cracow, PL;

Magdalena Strus, Cracow, PL;

Agnieszka Kyziol, Cracow, PL;

Diana Mikolajczyk, Cracow, PL;

Agnieszka Machul, Cracow, PL;

Assignees:

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Paris, FR;

UNIVERSITE D'ORLEANS, Orleans, FR;

JAGIELLONIAN UNIVERSITY, Cracow, PL;

Attorney:

Young & Thompson

Primary Examiner:

Paul V Ward

Int. Cl.
CPC ...
C07D 207/12 (2006.01); C07D 471/04 (2006.01); C07D 211/46 (2006.01); A01N 43/36 (2006.01); A01N 43/40 (2006.01); A01N 43/90 (2006.01); A61K 31/40 (2006.01); A61K 31/437 (2006.01); A61K 31/445 (2006.01); A61K 31/551 (2006.01); C07D 211/40 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A01N 43/36 (2013.01); A01N 43/40 (2013.01); A01N 43/90 (2013.01); A61K 31/40 (2013.01); A61K 31/437 (2013.01); A61K 31/445 (2013.01); A61K 31/551 (2013.01); C07D 207/12 (2013.01); C07D 211/40 (2013.01); C07D 211/46 (2013.01); C07D 487/04 (2013.01);
Abstract

The present invention relates to compounds of the following formula (I), wherein: m represents an integer being equal to 0, 1, 2, 3, 4, 5 or 6, X represents a simple bond or a radical —CHRwherein Rrepresents:—a hydrogen atom, or—a linear or branched, possibly interrupted by up to 3 heteroatoms selected from O, S or N and/or possibly substituted, (C-C)-alkyl, R, Rand Rrepresent independently from each other:—a hydrogen atom, or—a linear or branched (C-C-alkyl or (C-C)-acyl R5 represents:—a hydrogen atom, or—a linear or branched, possibly substituted, (C-C)-alkyi possibly substituted and possibly interrupted by up to 3 heteroatoms selected from O, S or N, Rrepresents:—a hydrogen atom, or—a linear or branched possibly substituted (C-C)-alkyl, possibly substituted and possibly interrupted by up to 3 heteroatoms selected from O, S or N, for their use as antibacterial drugs for the treatment and/or the prevention of infection(s) caused by biofilm-forming bacteria.

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