The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Apr. 03, 2015
Applicant:

Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, IN;

Inventors:

Govindaraju Thimmaiah, Bangalore, IN;

Nagarjun Narayanaswamy, Bangalore, IN;

Kolla Rajasekhar, Bangalore, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/14 (2006.01); C12Q 1/68 (2018.01); C07D 405/06 (2006.01); C07D 417/06 (2006.01); C07D 277/64 (2006.01); C07D 413/06 (2006.01); C07D 421/06 (2006.01); C09B 23/10 (2006.01); C12Q 1/6818 (2018.01); C12Q 1/6883 (2018.01); G01N 21/64 (2006.01); G01N 33/58 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); C07D 277/64 (2013.01); C07D 405/06 (2013.01); C07D 413/06 (2013.01); C07D 417/06 (2013.01); C07D 421/06 (2013.01); C09B 23/105 (2013.01); C12Q 1/6818 (2013.01); C12Q 1/6883 (2013.01); G01N 21/6428 (2013.01); G01N 33/582 (2013.01); G01N 33/6896 (2013.01); G01N 2021/6439 (2013.01); G01N 2333/4709 (2013.01); G01N 2800/2821 (2013.01);
Abstract

The present disclosure relates to compounds which function as small molecule fluorescent probes which aid in recognition of specific sequences in DNA and detection of Aβ aggregates. Probes/dyes of the instant disclosure are specific to AT-rich sequences of DNA and Aβ aggregates. These small organic dyes/probes are capable of exhibiting switch-on fluorescence and play an important role in fluorescence spectroscopy, diagnostics, imaging and biomedical applications.


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