The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Jul. 29, 2016
Applicants:

Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Lianyungang, Jiangsu Province, CN;

Lianyungang Runzhong Pharmaceutical Co., Ltd., Lianyungang, Jiangsu Province, CN;

Centaurus Biopharma Co., Ltd., Beijing, CN;

Inventors:

Na Zhao, Beijing, CN;

Shulong Wang, Beijing, CN;

Xijie Liu, Beijing, CN;

Yuandong Hu, Beijing, CN;

Hui Zhang, Beijing, CN;

Hong Luo, Beijing, CN;

Yong Peng, Beijing, CN;

Yongxin Han, Beijing, CN;

Xiquan Zhang, Lianyunganag, CN;

Hongjiang Xu, Lianyungang, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); A61P 35/00 (2006.01); A61K 31/53 (2006.01); C07D 251/26 (2006.01); C07D 251/18 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/53 (2013.01); A61P 35/00 (2018.01); C07D 251/18 (2013.01); C07D 251/26 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01);
Abstract

Disclosed are compounds having formulae I and II or pharmaceutically acceptable salts or hydrates thereof, a preparation method thereof and pharmaceutical compositions thereof. The compounds having formulae I and II possesses an isocitrate dehydrogenase 2 (IDH2) inhibitory activity and are capable of treating IDH2 mutation-induced cancers.


Find Patent Forward Citations

Loading…