The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 2020
Filed:
Nov. 02, 2007
James Dodge, Worcester, MA (US);
Lamya Shihabuddin, Brighton, MA (US);
Marco Passini, Shrewsbury, MA (US);
Seng H. Cheng, Wellesley, MA (US);
Catherine O'riordan, Waban, MA (US);
James Dodge, Worcester, MA (US);
Lamya Shihabuddin, Brighton, MA (US);
Marco Passini, Shrewsbury, MA (US);
Seng H. Cheng, Wellesley, MA (US);
Catherine O'Riordan, Waban, MA (US);
GENZYME CORPORATION, Cambridge, MA (US);
Abstract
This disclosure provides methods and compositions for treating disorders or injuries that affect motor function and control in a subject. In one aspect, the invention provides a method to deliver a transgene to a subject's spinal cord by administering a recombinant neurotropic viral vector containing the transgene. The viral vector delivers the transgene to a region of the deep cerebellar nuclei region of the brain. Also provided are compositions and methods to deliver a transgene to a subject's spinal cord by administering a recombinant neurotropic viral vector containing the transgene to the motor cortex region of the subject's brain.