The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Jun. 20, 2016
Applicant:

Bayer Pharma Aktiengesellschaft, Berlin, DE;

Inventors:

Hans-Georg Lerchen, Leverkusen, DE;

Anne-Sophie Rebstock, Champagne au Mont d'Or, FR;

Yolanda Cancho Grande, Leverkusen, DE;

Sven Wittrock, Berlin, DE;

Beatrix Stelte-Ludwig, Wülfrath, DE;

Christoph Mahlert, Wuppertal, DE;

Simone Greven, Dormagen, DE;

Stephan Märsch, Cologne, DE;

Dennis Kirchhoff, Berlin, DE;

Assignee:
Attorney:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61K 31/4025 (2006.01); A61K 38/00 (2006.01); A61P 35/00 (2006.01); C07D 207/33 (2006.01); A61K 31/40 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6803 (2017.08); A61K 31/40 (2013.01); A61K 31/4025 (2013.01); A61K 47/6849 (2017.08); A61K 47/6851 (2017.08); A61P 35/00 (2018.01); C07D 207/33 (2013.01); C07K 16/2866 (2013.01); A61K 2039/505 (2013.01); A61K 2039/572 (2013.01); C07K 2317/24 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present application relates to novel binder drug conjugates (ADCs), to active metabolites of these ADCs, to processes for preparing these ADCs, to the use of these ADCs for the treatment and/or prophylaxis of diseases and to the use of these ADCs for preparing medicaments for treatment and/or prophylaxis of diseases, in particular hyperproliferative and/or angiogenic disorders such as, for example, cancer diseases. Such treatments can be effected as monotherapy or else in combination with other medicaments or further therapeutic measures.


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