The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 2020
Filed:
Jul. 11, 2017
Applicant:
Janssen Vaccines & Prevention B.v., Leiden, NL;
Inventors:
Marija Vujadinovic, Leiden, NL;
Taco Gilles Uil, Amsterdam, NL;
Koen Oosterhuis, Haarlem, NL;
Jort Vellinga, Leiden, NL;
JerĂ´me Hubertina Henricus Victor Custers, Alphen aan den Rijn, NL;
Assignee:
Janssen Vaccines & Prevention B.V., Leiden, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); C07K 14/025 (2006.01); C07K 14/005 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); C07K 14/005 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/575 (2013.01); A61K 2039/645 (2013.01); A61K 2039/70 (2013.01); C07K 2319/00 (2013.01); C12N 2710/10022 (2013.01); C12N 2710/10042 (2013.01); C12N 2710/20034 (2013.01);
Abstract
The present invention relates to novel vaccines against Human papillomavirus (HPV) infections, based on recombinant capsid-display adenovirus vectors. Described are capsid modified replication deficient adenovirus particles encoding and displaying multiple HPV L2 antigenic fragments, via a minor capsid protein IX, and their use for eliciting an immune response in order to provide protection against infections from multiple HPV types.