The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Sep. 18, 2015
Applicant:

The Provost, Fellows, Foundation Scholars, & the Other Members of Board, of the College of the Holy, Dublin, IE;

Inventors:

Seamus J. Martin, Dublin, IE;

Conor Henry, Dublin, IE;

Graeme Sullivan, Dublin, IE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/06 (2006.01); A61K 38/07 (2006.01); A61K 38/05 (2006.01); A61K 38/55 (2006.01); A61K 31/10 (2006.01); A61K 31/496 (2006.01); A61K 31/137 (2006.01); A61K 31/19 (2006.01); A61K 31/713 (2006.01); A61K 31/277 (2006.01); A61K 31/495 (2006.01); C07K 16/24 (2006.01); A61K 39/395 (2006.01); A61K 31/222 (2006.01); A61K 31/675 (2006.01); A61K 38/00 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
A61K 38/07 (2013.01); A61K 31/10 (2013.01); A61K 31/137 (2013.01); A61K 31/19 (2013.01); A61K 31/222 (2013.01); A61K 31/277 (2013.01); A61K 31/495 (2013.01); A61K 31/496 (2013.01); A61K 31/675 (2013.01); A61K 31/713 (2013.01); A61K 38/005 (2013.01); A61K 38/05 (2013.01); A61K 38/06 (2013.01); A61K 38/55 (2013.01); A61K 39/3955 (2013.01); C07K 16/244 (2013.01); C07K 16/245 (2013.01); C07K 16/40 (2013.01);
Abstract

This invention relates to the use of an agent capable of inhibiting IL-36 proteolytic processing for the treatment and/or reduction of inflammation in a subject. Advantageously, the agent prevents the production of a biologically active IL-36 to prevent and/or reduce the pro-inflammatory effects of IL-36. The invention also relates to a method for treatment and/or reduction of inflammation and compositions for treating and/or reducing inflammation.


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