The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Jun. 03, 2018
Applicants:

The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, CN;

Guangzhou Institute of Respiratory Disease, Guangzhou, Guangdong, CN;

Inventors:

Kefang Lai, Guangdong, CN;

Xiaodong Liu, Guangdong, CN;

Bonian Zhong, Guangdong, CN;

Shan Zhong, Guangdong, CN;

Yichu Nie, Guangdong, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 36/00 (2006.01); A61K 31/715 (2006.01); A61K 36/268 (2006.01);
U.S. Cl.
CPC ...
A61K 31/715 (2013.01); A61K 36/268 (2013.01); A61K 2236/00 (2013.01); A61K 2236/30 (2013.01);
Abstract

The present invention discloses antotal polysaccharide extract with antitussive activity, an extraction method thereof and an application in the preparation of a medicine for preventing and treating coughs. The present invention proves that thetotal polysaccharide extract has a significant effect of suppressing cough for the first time through a large number of pharmacodynamic tests, has the therapeutic effect approximate to codeine, has the effect of prolonging the cough latent period better than codeine, and also finds that the totalpolysaccharide extract has the effects of reducing the cough sensitivity and suppressing the airway inflammation for the first time, has excellent preventive and therapeutic effects on various types of coughs, and can be used for preparing the medicines for preventing and treating cough-related diseases.


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