The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Mar. 24, 2015
Applicants:

Daniel Huang, Palo Alto, CA (US);

Nagaraja Rao, San Leandro, CA (US);

Trixie Tan, Belmont, CA (US);

Danforth Miller, San Carlos, CA (US);

Jeffry Weers, Belmont, CA (US);

Inventors:

Daniel Huang, Palo Alto, CA (US);

Nagaraja Rao, San Leandro, CA (US);

Trixie Tan, Belmont, CA (US);

Danforth Miller, San Carlos, CA (US);

Jeffry Weers, Belmont, CA (US);

Assignee:

Novartis AG, Basel, CH;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 9/00 (2006.01); A61K 38/13 (2006.01); A61K 31/436 (2006.01); A61K 31/4704 (2006.01); A61K 31/365 (2006.01); A61K 45/06 (2006.01); B01J 2/04 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5089 (2013.01); A61K 9/0075 (2013.01); A61K 9/5015 (2013.01); A61K 31/365 (2013.01); A61K 31/436 (2013.01); A61K 31/4704 (2013.01); A61K 38/13 (2013.01); A61K 45/06 (2013.01); B01J 2/04 (2013.01);
Abstract

Embodiments of the invention relate to particulate agents and compositions comprising particulate agents for inhalation, and methods for preparing such particulate agents and compositions for inhalation, as well as therapeutic methods. Embodiments of the method comprise preparing an emulsion by combining an oil phase dispersion of hydrophobic seed particles and an aqueous dispersion comprising an emulsifier and an emulsion stabilizer and preparing a feedstock comprising encapsulated particles by homogenizing the emulsion, and forming a plurality of coated particles by spray drying the feedstock, wherein resulting particles comprises a porous shell disposed on or over a core and the core comprises at least one hydrophobic seed particle.


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