The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Oct. 23, 2017
Applicant:

Ension, Inc., Pittsburgh, PA (US);

Inventors:

Ali Hussain, Cape Coral, FL (US);

Patrick Cahalan, Cape Coral, FL (US);

Linda Cahalan, Cape Coral, FL (US);

Assignee:

ENSION INC., Butler, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61F 13/00 (2006.01); C07K 14/78 (2006.01); A61L 15/32 (2006.01); A61L 15/42 (2006.01); A61L 27/20 (2006.01); B32B 5/10 (2006.01); A61K 38/39 (2006.01); A61L 27/24 (2006.01); A61L 31/14 (2006.01); A61L 31/04 (2006.01);
U.S. Cl.
CPC ...
A61F 13/00012 (2013.01); A61F 13/00029 (2013.01); A61K 38/39 (2013.01); A61L 15/325 (2013.01); A61L 15/425 (2013.01); A61L 27/20 (2013.01); A61L 27/24 (2013.01); A61L 31/044 (2013.01); A61L 31/146 (2013.01); B32B 5/10 (2013.01); C07K 14/78 (2013.01); A61F 2013/00604 (2013.01); B32B 2250/20 (2013.01);
Abstract

A method of preparing a crosslinked, collagen-based wound care dressing is provided, comprising: (a) immersing a sample of fibrous and/or non-fibrous collagen in a buffered acidic, aqueous solution comprising an alcohol; (b) contacting the collagen in solution with a catalytic component comprising 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride for a time at least sufficient to effect reaction between amino and carboxyl groups present on the collagen and to yield crosslinked collagen that is resistant to pronase degradation; and (c) drying the crosslinked collagen to yield a porous, crosslinked collagen article wherein the porous, crosslinked collagen article demonstrates a pore size of 10-500 microns. Also provided are bioactive collagen medical scaffolds for hernia repair prosthetics and surgical incision closure members, prepared using the method above.


Find Patent Forward Citations

Loading…