The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 2020

Filed:

Aug. 20, 2019
Applicant:

The General Hospital Corporation, Boston, MA (US);

Inventors:

Ramin Haghgooie, Arlington, AR (US);

Kenneth T. Kotz, Auburndale, MA (US);

Robert Granier, Boston, MA (US);

Anne Celia Petrofsky, Sudbury, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/03 (2006.01); G01N 21/11 (2006.01); G01N 21/25 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
G01N 21/03 (2013.01); B01L 3/5027 (2013.01); B01L 3/502723 (2013.01); G01N 21/11 (2013.01); G01N 21/253 (2013.01); B01L 2200/143 (2013.01); B01L 2200/146 (2013.01); B01L 2300/0851 (2013.01); B01L 2300/0858 (2013.01); B01L 2300/0877 (2013.01); B01L 2400/0622 (2013.01); G01N 2021/0346 (2013.01); G01N 2021/0357 (2013.01);
Abstract

Reusable network of spatially-multiplexed microfliuidic channels each including an inlet, an outlet, and a cuvette in-between. Individual channels may operationally share a main or common output channel defining the network output and optionally leading to a disposable storage volume. Alternatively, multiple channels are structured to individually lead to the storage volume. An individual cuvette is dimensioned to substantially prevent the formation of air-bubbles during the fluid sample flow through the cuvette and, therefore, to be fully filled and fully emptied. The overall channel network is configured to spatially lock the fluidic sample by pressing such sample with a second fluid against a closed to substantially immobilize it to prevent drifting due to the change in ambient conditions during the measurement. Thereafter, the fluidic sample is flushed through the now-opened valve with continually-applied pressure of the second fluid. System and method for photometric measurements of multiple fluid samples employing such network of channels.


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